PoE Synthesising Fragment: Uber Venarius

Synthesising Fragment is a map fragment in Path of Exile that grants access to the Uber Venarius encounter, a significantly more challenging version of the Cortex boss fight. This encounter is designed for players seeking an extreme challenge, with enhanced mechanics and heightened difficulty.

Synthesising Fragment

The price of Synthesising Fragment is about 11 Chaos Orbs.

Item Description

The Cortex: Level 85
Lore: “When memories become twisted by a corrupted mind, history is rewritten, time after time.”
Usage: Use five Synthesising Fragments in a personal Map Device to open portals to The Cortex. This item can only be used once.

Mechanics

When five Synthesising Fragments are placed into a Map Device, they open portals to the Uber Venarius encounter. This fight is a more challenging version of the standard Venarius fight in the Cortex, with several significant changes to the boss’s abilities and the fight’s overall difficulty.

Key Changes in the Uber Venarius Encounter:

Area Modifications:

Monsters take 70% less damage, greatly increasing the time and effort required to defeat enemies.
100% increased effect of Additional Modifiers, including random map mods and synthesis global mods, which can add significant difficulty.

Enhanced Venarius Abilities:

Additional Unique Synthetes: Each unique phase of the fight will spawn an additional Unique Synthete, which are powerful map bosses from Synthesis Maps. These bosses will persist between stages if not killed before the main boss.

Fractal Gargantuan — Altered Synthete
Synthete Masterpiece — Augmented Synthete
Fractal Titan — Twisted Synthete
Synthete Nightmare — Rewritten Synthete

Energy Pylons: These will spawn in all four unique phases, adding additional layers of complexity and danger to the encounter.

Uber Venarius Rewards

Defeating Uber Venarius offers the possibility of obtaining unique and powerful rewards, making the fight highly rewarding for those who can overcome the challenge.

Item Acquisition

Synthesising Fragments can be obtained from specific sources:

Drop Locations: This fragment has a chance to drop from Tier 17 map bosses, with a higher likelihood of dropping from the bosses of Abomination Map, Citadel Map, and Ziggurat Map.

Monsters: Synthesising Fragments can also be acquired from specific monsters in Nightmare variants of boss encounters, such as:

Nightmare of Catarina
Nightmare of Lycia
Nightmare of the Depraved Trinity
Nightmare of the Unbreakable
Nightmare of Uhtred

Conclusion

The Uber Venarius encounter, unlocked by using Synthesising Fragments, presents one of the most challenging experiences in Path of Exile. With its enhanced mechanics and increased difficulty, it is designed to test even the most skilled players. The potential rewards make this fight both challenging and highly rewarding for those who can successfully complete it.

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