PoE 2 Multiple Poison – Path of Exile 2

PoE 2 Multiple Poison

It is a Support Gem.

Support
Chaos
Tier: 1
Requires: Level 1
Support Reqirements: +5 Dex

Supports any skill that Hits enemies, allowing it to inflict an extra Poison an enemies but shortening the duration of those Poisons.

  • Supported Skills can Poison enemies an additional time
  • Supported Skills have 30% less Poison Duration

Place into a Skill’s Support Gem socket in the Skills menu to apply its effects to that Skill. You cannot have multiple copies of the same Support Gem socketed at the same time.

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The Multiple Poison Support Gem is a valuable tool for chaos-based builds in Path of Exile 2, enhancing poison-focused skills by allowing them to apply an additional stack of poison to enemies. However, this comes at the cost of reducing the duration of poison effects. This trade-off makes it an excellent choice for fast-paced, high-damage builds that aim to overwhelm enemies with multiple poison applications in quick succession.

Gem Details

  • Category: Support
  • Tier: 1
  • Required Level: 1
  • Support Requirements: +5 Dexterity
  • Effects:
    • Supported Skills can Poison enemies an additional time.
    • Supported Skills have 30% less Poison Duration.
    • Place into a Skill’s Support Gem socket in the Skills menu to apply its effects to that skill.
    • You cannot have multiple copies of the same Support Gem socketed at the same time.

How Multiple Poison Works

  1. Additional Poison Applications:

    • Supported skills can apply an additional stack of poison each time they poison an enemy. This significantly increases the poison stacks over a short duration.

  2. Reduced Poison Duration:

    • The duration of each poison effect is reduced by 30%, requiring rapid applications to maintain high poison damage.

  3. Effect on Chaos Damage:

    • Multiple poison applications result in a cumulative increase in chaos damage over time, especially for skills with high hit rates or multiple projectiles.

Advantages of Multiple Poison Support

  1. Increased Poison Damage Output:

    • Doubling the poison stacks on each hit amplifies the overall damage output, making it ideal for fast-hitting or multi-hit skills.

  2. Synergy with Poison Mechanics:

    • Works well with builds that already scale poison damage through passives, gear, or other support gems.

  3. Faster Enemy Takedown:

    • The increased poison stacks ensure quicker damage buildup, allowing players to defeat enemies faster, especially in boss fights or crowd-heavy scenarios.

Challenges and Considerations

  1. Shorter Poison Duration:

    • The 30% reduction in poison duration requires consistent and frequent poison applications to maintain maximum damage output.

  2. Socket Investment:

    • Using this support gem takes up a valuable socket, potentially competing with other crucial support gems.

  3. Synergy Dependence:

    • Best suited for builds that already heavily invest in poison mechanics, making it less effective in generic builds.

Best Builds for Multiple Poison Support

  1. Chaos-Assassin Builds:

    • Builds utilizing skills like Viper Strike or Poisonous Concoction benefit significantly from the additional poison stacks.

  2. Ranged Chaos Builds:

    • Projectile-based skills like Caustic Arrow or Toxic Rain can apply poison rapidly to multiple targets.

  3. Fast-Attack Speed Builds:

    • Builds with high attack or cast speed maximize poison stack applications, leveraging the gem’s strengths.

  4. Multi-Projectile Builds:

    • Skills that fire multiple projectiles, such as Rain of Arrows, can quickly stack poison on groups of enemies.

Synergies and Combinations

  1. Poison Duration Scaling:

    • Pair with passives or items that increase poison duration to offset the gem’s penalty.

  2. Chaos Damage Scaling:

    • Combine with gems like Deadly Ailments or Void Manipulation for maximum poison damage.

  3. Hit Frequency:

    • Use with skills like Blade Vortex or Cobra Lash that hit frequently, ensuring rapid poison application.

  4. Support Gems:

    • Add Lesser Poison or Chance to Poison to ensure consistent poison application across skills.

Example Playstyle

  • Equip Multiple Poison Support with a skill like Blade Vortex or Toxic Rain, ensuring high hit frequency for maximum poison stack application.
  • Focus on scaling attack or cast speed to make the most of the gem’s effect.
  • Use additional supports, such as Unbound Ailments or Increased Area of Effect, to enhance the build’s overall effectiveness.

Conclusion

The Multiple Poison Support Gem is a powerful option for poison-centric builds in Path of Exile 2, offering the ability to dramatically increase poison stacks and damage output. While the reduced poison duration demands frequent application, the trade-off is worth it for builds that can sustain a high hit rate.

If your build revolves around chaos damage and poison mechanics, Multiple Poison Support is an essential tool for maximizing your potential, ensuring your enemies succumb to a torrent of deadly toxins.

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